Bozitinib, CAS 1440964-89-5

Product Description: Bozitinib (PLB-1001) is a highly selective c-MET kinase inhibitor with blood-brain barrier permeability. Bozitinib (PLB-1001) is a ATP-competitive small-molecule inhibitor, binds to the conventional ATP-binding pocket of the tyrosine kinase superfamily[1].

Applications: Cancer-Kinase/protease

Formula: C20H15F3N8

References: [1]Hu H, et al. Mutational Landscape of Secondary Glioblastoma Guides MET-Targeted Trial in Brain Tumor. Cell. 2018 Nov 29;175(6):1665-1678.e18.

CAS Number: 1440964-89-5

Molecular Weight: 424.38

Compound Purity: 98.98

Research Area: Cancer

Solubility: DMSO : 50 mg/mL (ultrasonic)

Target: c-Met/HGFR

• SKU: MEXHY-125017-10.1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-125017-10.1
• Package Unit: 10 mM/1 ml
• Quantity Unit: STK