bpV(HOpic) (potassium salt) (technical grade), CAS 722494-26-0

Shelf life (days): 1460.0

Formulation: A crystalline solid

Formal Name: (5-hydroxy-2-pyridinecarboxylato-?N1,?O2)oxodiperoxy-vanadate(2-), dipotassium

Purity: ≥80%

Formula Markup: C6H4NO8V / 2K

Formula Weight: 347.2

CAS Number: 722494-26-0

Notes: bpV(HOpic) is a bisperoxovanadium (bpV) compound that inhibits several different protein tyrosine phosphatases (PTPs), with selectivity for PTEN (IC50 = 14 nM).{22177} It also inhibits the vascular endothelial PTP, PTP-β (IC50 = 4.9 μM), and PTP-1βB (IC50 = 25.3 μM).{22177} At 15 μM, bpV(HOpic) has been shown to protect against stimulated ischemia-reperfusion injury in vitro by decreasing apoptosis and improving cell viability through the upregulation of the PI3K/Akt/eNOS/ERK prosurvival pathway.{22541}

• SKU: CAY15438-25
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 15438-25
• Package Unit: 25 mg
• Quantity Unit: STK