BRD5080

Product Description: BRD5080 is a potent GPR65 positive allosteric modulator. BRD5080 induces GPR65-dependent cAMP production. BRD5080 exhibits a robust induction of cAMP activity and recruits G protein for the WT and variant hGPR65 as well as for the mouse ortholog. BRD5080 has the potential for autoimmune and inflammatory diseases research[1].

Applications: COVID-19-immunoregulation

Formula: C24H23FN4O3

References: [1]Ilona Neale, et al. Small-molecule probe for IBD risk variant GPR65 I231L alters cytokine signaling networks through positive allosteric modulation. Sci Adv. 2024 Jul 19;10(29):eadn2339.

Molecular Weight: 434.46

Research Area: Inflammation/Immunology

Target: Others

• SKU: MEXHY-162735-100
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-162735-100
• Package Unit: 100 mg
• Quantity Unit: STK