Product Description: BRD73954 is a potent HDAC inhibitor and selectively inhibiting both HDAC6 and HDAC8 with IC50 values of 0.0036, 0.12, 9, 12, 23 μM for HDAC6, HDAC8, HDAC2, HDAC1 and HDAC3, respectively. BRD73954 decreases the levels of HDAC6, associated with upregulation of Ac-Tubulin[1].
Applications: Cancer-programmed cell death
Formula: C16H16N2O3
References: [1]Olson DE, et, al. Discovery of the first histone deacetylase 6/8 dual inhibitors. J Med Chem. 2013 Jun 13;56(11):4816-20.
CAS Number: 1440209-96-0
Molecular Weight: 284.31
Compound Purity: 98.0
Research Area: Cancer
Solubility: DMSO : 25 mg/mL (ultrasonic)
Target: HDAC