Brilanestrant, CAS 1365888-06-7

Product Description: Brilanestrant (ARN-810; GDC-0810) is an orally bioavailable selective estrogen receptor degrader (SERD) with IC50 of 0.7 nM.

Applications: Cancer-programmed cell death

Formula: C26H20ClFN2O2

References: [1]By Lai, et al. Identification of GDC-0810 (ARN-810), an Orally Bioavailable Selective Estrogen Receptor Degrader (SERD) that Demonstrates Robust Activity in Tamoxifen-Resistant Breast Cancer Xenografts. J Med Chem. 2015 Jun 25;58(12):4888-904./[2]Joseph JD, et al. The selective estrogen receptor downregulator GDC-0810 is efficacious in diverse models of ER+ breast cancer. Elife. 2016 Jul 13;5. pii: e15828. doi: 10.7554/eLife.15828

CAS Number: 1365888-06-7

Molecular Weight: 446.90

Compound Purity: 99.95

Research Area: Cancer

Solubility: DMSO : 100 mg/mL (ultrasonic)

Target: Estrogen Receptor/ERR

• SKU: MEXHY-12864-10.1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-12864-10.1
• Package Unit: 10 mM/1 ml
• Quantity Unit: STK