BTB-1, CAS 86030-08-2

Shelf life (days): 1460.0

Formulation: A crystalline solid

Formal Name: 4-chloro-2-nitro-1-(phenylsulfonyl)-benzene

Purity: ≥98%

Formula Markup: C12H8ClNO4S

Formula Weight: 297.71496

CAS Number: 86030-08-2

Notes: BTB-1 is a reversible inhibitor of the kinesin-8 family motor protein Kif18A (IC50 = 1.69 μM).{46312} It is selective for Kif18A over a panel of seven kinesins at 100 μM. BTB-1 (100 μM) inhibits Kif18A-dependent microtubule motility in a microtubule gliding assay. It induces mitotic accumulation of HeLa cells in a dose-dependent manner.

• SKU: CAY27219-1
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 27219-1
• Package Unit: 1 g
• Quantity Unit: STK