BTK ligand 1, CAS 330785-90-5

Product Description: BTK ligand 1 (compound 1) is a ligand targeting Bruton’s tyrosine kinase (Btk). BTK ligand 1 can combine with E3 ligase ligand (Ligand for E3 Ligase) through PROTAC Linker to form PROTAC. PROTACs targeting Btk can be used in the study of chronic lymphocytic leukemia (CLL) and other BK cell malignancies[1].

Applications: Cancer-Kinase/protease

Formula: C22H22N6O

References: [1]Buhimschi AD, et al. Targeting the C481S Ibrutinib-Resistance Mutation in Bruton's Tyrosine Kinase Using PROTAC-Mediated Degradation. Biochemistry. 2018 Jul 3;57(26):3564-3575.

CAS Number: 330785-90-5

Molecular Weight: 386.45

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: Btk;Ligands for Target Protein for PROTAC

• SKU: MEXHY-150885-1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-150885-1
• Package Unit: 1 mg
• Quantity Unit: STK