BTSA1, CAS 314761-14-3

Product Description: BTSA1 is a potent, high affinity and orally active BAX activator with an IC50 of 250 nM and an EC50 of 144 nM. BTSA1 binds with high affinity and specificity to the N-terminal activation site and induces conformational changes to BAX leading to BAX-mediated apoptosis[1].

Applications: Cancer-programmed cell death

Formula: C21H14N6OS2

References: [1]Reyna DE, et al. Direct Activation of BAX by BTSA1 Overcomes Apoptosis Resistance in Acute Myeloid Leukemia. Cancer Cell. 2017 Oct 9;32(4):490-505.e10.

CAS Number: 314761-14-3

Molecular Weight: 430.51

Compound Purity: 99.49

Research Area: Cancer

Solubility: DMSO : 25 mg/mL (ultrasonic)

Target: Apoptosis;Bcl-2 Family

• SKU: MEXHY-123054-10.1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-123054-10.1
• Package Unit: 10 mM/1 ml
• Quantity Unit: STK