BU 224 (hydrochloride), CAS 205437-64-5

Shelf life (days): 1460.0

Formulation: A solid

Formal Name: 2-(4,5-dihydro-1H-imidazol-2-yl)-quinoline, monohydrochloride

Purity: ≥95%

Formula Markup: C12H11N3 / HCl

Formula Weight: 233.7

CAS Number: 205437-64-5

Notes: An imidazoline receptor agonist; selectively binds to imidazoline I1 and -I2 receptors over a2-ARs (IC50s = 0.034, 0.026, and 15 µM, respectively); reduces complete Freund’s adjuvant-induced thermal and mechanical hyperalgesia in rats at 10 or 17.8 mg/kg; decreases the latency to seizure onset and increases the percentage of animals with grade V seizures to a greater extent in female than male mice; reverses cognitive deficits in the 5XFAD transgenic mouse model of Alzheimer’s disease at 5 mg/kg

• SKU: CAY42451-5
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 42451-5
• Package Unit: 5 mg
• Quantity Unit: STK