Target Synonym: Intestinal Peptide-Associated Transporter HPT;Cadherin;CDH;HPT;CDH17;CDH16;HPT-1;HPT1;Cadherin-17;Intestinal Peptide-Associated Transporter HPT-1;LI-Cadherin;Liver-Intestine Cadherin
Background: This gene is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. The encoded protein is cadherin-like, consisting of an extracellular region, containing 7 cadherin domains, and a transmembrane region but lacking the conserved cytoplasmic domain. The protein is a component of the gastrointestinal tract and pancreatic ducts, acting as an intestinal proton-dependent peptide transporter in the first step in oral absorption of many medically important peptide-based drugs. The protein may also play a role in the morphological organization of liver and intestine. Alternative splicing results in multiple transcript variants.
Immunogen: Recombinant Human Cadherin-17 / LI-cadherin / CDH17 protein
Buffer: 0.2 μm filtered solution in PBS
Dilution: IHC-P 1:50-1:200;
English
Deutsch
