Description: Carbendazim (Mercarzole) is a broad-spectrum benzimidazole antifungal with potential antimitotic and antineoplastic activities. Although the exact mechanism of action is unclear, carbendazim appears to binds to an unspecified site on tubulin and suppresses microtubule assembly dynamic. This results in cell cycle arrest at the G2/M phase and an induction of apoptosis.
CAS Number: 10605-21-7
Formula: C9H9N3O2
Molecular Weight: 191,19
References: Jiang J, et al. Toxicol In Vitro. 2015 Oct;29(7):1473-81.