Shelf life (days): 1460.0
Formulation: A crystalline solid
Formal Name: (3ß,20ß)-3-(3-carboxy-1-oxopropoxy)-11-oxo-olean-12-en-29-oic acid, disodium salt
Purity: ≥98%
Formula Markup: C34H48O7 / 2Na
Formula Weight: 614.72026
CAS Number: 7421-40-1
Notes: Carbenoxolone is a derivative of β-glycyrrhetinic acid (Item No. 11845), a major metabolite of glycyrrhizin, one of the main constituents of licorice. Similar to β-glycyrrhetinic acid and glycyrrhizin, carbenoxolone has been shown to exhibit anti-ulcerative and anti-inflammatory properties.{29513} Carbenoxolone inhibits 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1; Item No. 10007815) conversion of cortisol to cortisone, which contributes to its potential to induce mineralocorticoid hypertension.{11854} It is also reported to inhibit 11β-HSD2 conversion of cortisone to cortisol resulting in improved cognitive and neuroprotective effects.{24097}
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