Clone Name: M155
Calculated MW: 24
Specificity/Sensitivity: No cross-reactivity with skeletal muscle TnI.
Form: Liquid
Buffer (with preservative): PBS, 0.09% Sodium azide.
Concentration: Batch dependent (Please refer to the vial label for the specific concentration.)
Background: Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. This gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in this gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM). [provided by RefSeq, Jul 2008]
Uniprot ID: P19429
Antigen Species: Human
Immunogen: Free human cardiac troponin I, native human cardiac troponin complex, or human cardiac troponin I peptides.
Purification: Protein A purified
Conjugation: Unconjugated
Full Name: troponin I3, cardiac type
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