Caspase 9 Activity Detection Substrate for Flow Cytometry

Caspase 9 Activity Detection Substrate for Flow Cytometry
SKU
ELSE-CK-A489-20
Packaging Unit
20 Tests
Manufacturer
Elabscience Biotechnology

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Tested Sample Types: Cell samples

Assay Time: 30 min

Type: Apoptosis/Caspase

Test Principle: Fluorometric method;Flow cytometry, The Caspase 9 Activity Detection Substrate for Flow Cytometry are a novel fluorogenic dye that couple the caspase 9 recognition sequence (LEHD) to a high affinity DNA dye, which have cell membrane permeability and can penetrate the plasma membrane into the cytoplasm. The substrate itself has no fluorescence and has a charge exclusion effect with DNA. During cell apoptosis, caspase-9 cleaves the substrate and releases high affinity DNA dyes, which bind to DNA to produce strong fluorescence, thereby detecting caspase-9 activity and visualizing the morphological changes of the cell nucleus during apoptosis.
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SKU ELSE-CK-A489-20
Manufacturer Elabscience Biotechnology
Manufacturer SKU E-CK-A489-20
Package Unit 20 Tests
Quantity Unit PAK
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