Shelf life (days): 1460.0
Formulation: A solid
Formal Name: 1-[(4R,5S)-5-[(2-aminoethyl-1,1,2,2-d4)amino]-N2-(10,12-dimethyl-1-oxotetradecyl)-4-hydroxy-L-ornithine]-5-[(3R)-3-hydroxy-L-ornithine]-pneumocandin B0, diacetate
Purity: ≥99% deuterated forms (d1-d4)
Formula Markup: C52H84D4N10O15 / 2C2H4O2
Formula Weight: 1217.5
Notes: Caspofungin-d4 (acetate) is intended for use as an internal standard for the quantification of caspofungin (Item No. 15923) by GC- or LC-MS. Caspofungin is an antifungal compound that is classified as an echinocandin, as it acts by noncompetititvely inhibiting the enzyme 1,3-β glucan synthase and preventing the synthesis of glucan in the fungal cell wall.{26520} It is effective against disseminated or invasive aspergillosis and candidiasis.{26517,26521} Caspofungin has a 50% minimum effective concentration against Aspergillus spp. of 0.015 µg/ml.{26518} It does not antagonize other antifungal compounds, like amphotericin B, and, in some cases, may show additive or synergistic activity.{26520,26521,20805}
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