Shelf life (days): 1460.0
Formulation: A crystalline solid
Formal Name: N-[4-oxo-4-[(2-phenylethyl)amino]butyl]-carbamic acid, ethyl ester
Purity: ≥95%
Formula Markup: C15H22N2O3
Formula Weight: 278.4
CAS Number: 1477949-42-0
Notes: CAY10683 is a potent histone deacetylase (HDAC) inhibitor isolated from the cyanobacterium Symploca.{24818} It inhibits HDAC2 and HDAC6 with IC50 values of 0.119 and 434 nM, respectively, and is without effect against HDAC4 (IC50 = >1,000 nM).{24818} CAY10683 inhibits the growth of HCT116 colon cancer cells and HuT-78 cutaneous T cell lymphoma cells (GI50 = 29.4 and 1.4 μM, respectively) more effectively than human dermal fibroblasts (GI50 = >100 μM).{24818}