CB-5339, CAS 1863952-15-1

Product Description: CB-5339 is an oral activity potent p97 inhibitor with an IC50 [1]. CB-5339 extracted from WO2015109285A1 compound FF07.

Applications: Cancer-programmed cell death

Formula: C24H24N6O

References: [1]David Wustrow, et al. FUSED PYRIMIDINES AS INHIBITORS OF p97 COMPLEX. WO2015109285A1./[2]Roux B, et.al. Targeting acute myeloid leukemia dependency on VCP-mediated DNA repair through a selective second-generation small-molecule inhibitor. Sci Transl Med. 2021 Mar 31;13(587):eabg1168.

CAS Number: 1863952-15-1

Molecular Weight: 412.49

Compound Purity: 99.58

Research Area: Cancer

Solubility: DMSO : 100 mg/mL (ultrasonic;warming;heat to 80°C)

Target: p97

• SKU: MEXHY-128724-10.1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-128724-10.1
• Package Unit: 10 mM/1 ml
• Quantity Unit: STK