Clone: DJ130c
Specificity: Recognizes human CD16, a 50-65kD cell surface molecule, which is the low affinity receptor for IgG (FcR III). CD16 exists as a transmembranous form (Fc gammaRIIIA, or CD16A) and a glycosyl phosphatidylinositol (GPI) anchored form (Fc gammaRIIIB, or CD16B). CD16A is expressed by NK cells, some T cells, and macrophages, whereas CD16B is primarily expressed by granulocytes. In addition, CD16B exists as two allelic variants NA1 and NA2. Recognizes all polymorphonuclear cells irrespective on their NA phenotype. Studies show that the Recognizes an epitope in the first membrane-distal domain of Recognizes both CD16A and CD16B.
Antibody Modification: Biotin
Presentation: PBS, 0.09% Sodium Azide, 1% BSA
Immunogen: CD34 antigen
Gene: CD16
Description: CD16 antibody LS-C44951 is a biotin-conjugated mouse monoclonal antibody to human CD16. Validated for Flow.
Usage: Flow Cytometry: Use 10 ul of the suggested working dilution to label 1x10^6 cells in 100 ul. Method sheets are available on request. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
Recommended Storage: Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.
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