Target Synonym: GIG;MORT;Hematopoietic progenitor cell antigen CD;Gp105;CD34;CD34 molecule;GIG3;MORT1;Gp105-120;My10;Hematopoietic progenitor cell antigen CD34;Mucosialin;CD34;CD34 molecule;GIG3;MORT1;RP11-328D5.2
Background: CD34, also known as gp105-120, is a type I monomeric sialomucin-like glycophosphoprotein with an approximate molecular weight of 105-120 kD. Selectively expressed on the majority of hematopoietic stem/progenitor cells, bone marrow stromal cells, capillary endothelial cells, embryonic fibroblasts, and some nervous tissue, CD34 is a commonly used marker to identify human hematopoietic stem/progenitor cells. According to the differential sensitivity to enzymatic cleavage, four groups of epitopes of CD34 have been described. CD34 mediates cell adhesion and lymphocytes homing through binding to L-selectin and E-selectin ligands.
Immunogen: Full length human CD34 expression plasmid
Buffer: 0.2 μm filtered solution in PBS
Dilution: WB 1:500-1:2000;IP 1-5 μL/mg of lysate
Calculated MW: 41 kDa
Observed MW: 95 kDa
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