CD82/KAI-1 Monoclonal Antibody

Target Synonym: SAR;TSPAN274F;Tetraspanin;CD82 antigenC;Inducible membrane protein R;KAI1GR;ST6tspan;KAI;CD82;4F9;C33;GR15;IA4;KAI1;R2;SAR2;ST6;TSPAN27;CD82 antigenC33;CD82 molecule;IA4C33 antigen;Inducible membrane protein R2;KAI-1;KAI1GR15;ST6tspan-27;Suppressor of tumorigenicity 6 protein;Tetraspanin-27;Tspan-27;TSPAN274F9;4F9;C33;Kai1

Background: This metastasis suppressor gene product is a membrane glycoprotein that is a member of the transmembrane 4 superfamily. Expression of this gene has been shown to be downregulated in tumor progression of human cancers and can be activated by p53 through a consensus binding sequence in the promoter. Its expression and that of p50 are strongly correlated, and the loss of expression of these two proteins is associated with poor survival for prostate cancer patients. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Immunogen: Recombinant Human CD82 / KAI-1 protein

Buffer: 0.2 μm filtered solution in PBS

Dilution: IHC-P 1:50-1:200;

• SKU: ELSAN200127P-100
• Manufacturer: Elabscience Biotechnology
• Manufacturer SKU: AN200127P-100
• Package Unit: 100μL
• Quantity Unit: STK
• Reactivity: Human
• Clonality: Monoclonal
• Application: Immunohistochemistry (paraffin)
• Isotype: IgG1
• Host: Mouse
• Conjugate: Unconjugated