CD98(UM7F8), 1mg/mL

Description: CD98 exits as a heterodimer containing a disulphide-linked glycosylated heavy chain and a non-glycosylated light chain. It is a member of the solute carrier family and encodes a cell surface, transmembrane protein. The protein exists as the heavy chain of a heterodimer, covalently bound through disulfide bonds to one of several possible light chains. The encoded transporter plays a role in regulation of intracellular calcium levels and transports L-type amino acids. Alternatively spliced transcript variants, encoding different isoforms, have been characterized.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Product Origin: Animal - Mus musculus (mouse)

Conjugate: Purified, BSA-free

Concentration: 1 mg/mL

Storage buffer: PBS, no BSA, no azide

Clone: UM7F8

Immunogen: Molt 13 T cell line

Antibody Reactivity: CD98

References: Note: References for this clone sold by other suppliers may be listed for expected applications.

1. Cell Immunol (1994) 154(1):253-63. (IP, Flow, functional studies)
2. J Cell Biol (2001) 276(42): 39282-39289. (IF)
3. Leukocyte Typing V (S.F. Schlossman, et al, eds.) Oxford University Press, Oxford, (1995) p. 280-283.
4. Leukocyte Typing VI (T. Kishimoto, et al, eds.) Garland Publishing, Inc., New York (1997) p. 531-534.

Entrez Gene ID: 6520

Expected AB Applications: Flow, surface (published for clone)/Functional studies (published for clone)/IF (published for clone)/IP (published for clone)

Z-Antibody Applications: Flow, surface (published)/IF (published)/Functional studies (published)/IP (published)

Antibody Application Notes: Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody/Flow Cytometry 0.5-1 ug/million cells/0.1 mL/Immunofluorescence 0.5-1.0 ug/mL/Comitogenic with soluble anti-CD2 and immobilized anti-CD3 mAbs/Optimal dilution for a specific application should be determined by user

• SKU: BTMBNUM0425-50
• Manufacturer: Biotium
• Manufacturer SKU: BNUM0425-50
• Package Unit: 50 µl
• Quantity Unit: STK
• Reactivity: Human
• Clonality: Monoclonal
• Application: Immunofluorescence, Immunoprecipitation, Flow Cytometry, Functional Studies
• Isotype: IgG1
• Host: Mouse
• Conjugate: Unconjugated