Product Description: CDDO-EA is an NF-E2 related factor 2/antioxidant response element (Nrf2/ARE) activator.
Applications: Cancer-programmed cell death
Formula: C33H46N2O3
References: [1]Neymotin A, et al. Neuroprotective effect of Nrf2/ARE activators, CDDO ethylamide and CDDO trifluoroethylamide, in a mouse model of amyotrophic lateral sclerosis. Free Radic Biol Med. 2011 Jul 1;51(1):88-96./[2]Liby K, et al. The synthetic triterpenoids CDDO-methyl ester and CDDO-ethyl amide prevent lung cancer induced by vinyl carbamate in A/J mice. Cancer Res. 2007 Mar 15;67(6):2414-9.
CAS Number: 932730-51-3
Molecular Weight: 518.73
Compound Purity: 99.71
Research Area: Cancer
Solubility: DMSO : 16.67 mg/mL (ultrasonic;warming;heat to 80°C)
Target: Keap1-Nrf2