CDE-096, CAS 1228357-04-7

Product Description: CDE-096 is a potent inhibitor of PAI-1. CDE-096 prevents PAI-1 from inactivating tPA and uPA with similar potency (IC50=30 and 25 nM, respectively) and is active against glycosylated PAI-1, as well as PAI-1 derived from several species (IC50=19, 22 and 18 nM for murine, rat, and Porcine PAI-1, respectively)[1].

Applications: Neuroscience-Neuromodulation

Formula: C25H20F3NO12

References: [1]Li SH, et al. Mechanistic characterization and crystal structure of a small molecule inactivator bound to plasminogen activator inhibitor-1. Proc Natl Acad Sci U S A. 2013;110(51):E4941-E4949.

CAS Number: 1228357-04-7

Molecular Weight: 583.42

Compound Purity: 99.97

Research Area: Cardiovascular Disease

Solubility: DMSO : 100 mg/mL (ultrasonic)

Target: PAI-1

• SKU: MEXHY-120516-10.1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-120516-10.1
• Package Unit: 10 mM/1 ml
• Quantity Unit: STK