Product Description: CDPPB is a potent, selective and brain penetrant positive allosteric modulator of the metabotropic glutamate receptor subtype 5 (mGluR5), with an EC50 of 27 nM in Chinese hamster ovary cells expressing human mGluR5. CDPPB may provide an approach for development of antipsychotic agents[1].
Applications: Neuroscience-Neuromodulation
Formula: C23H16N4O
References: [1]Kinney GG, et, al. A novel selective positive allosteric modulator of metabotropic glutamate receptor subtype 5 has in vivo activity and antipsychotic-like effects in rat behavioral models. J Pharmacol Exp Ther. 2005 Apr; 313(1):199-206.
CAS Number: 781652-57-1
Molecular Weight: 364.40
Compound Purity: 99.32
Research Area: Neurological Disease
Solubility: DMSO : 100 mg/mL (ultrasonic)
Target: mGluR