CDX-3379

Product Description: CDX-3379 is a humanized monoclonal antibody inhibitor targeting ErbB3. CDX-3379 binds to ErbB3, blocking the dimerization of ErbB3 with other receptors, thereby inhibiting the phosphorylation of ErbB3. CDX-3379 can inhibit the growth and proliferation of tumor cells. CDX-3379 is promising for research of tumors expressing ErbB3 and NRG1, such as HNSCC[1].

Formula: N/A

References: [1]Duvvuri U, et al. Molecular and Clinical Activity of CDX-3379, an Anti-ErbB3 Monoclonal Antibody, in Head and Neck Squamous Cell Carcinoma Patients. Clin Cancer Res. 2019 Oct 1;25(19):5752-5758.

Molecular Weight: N/A

Research Area: Cancer

Target: EGFR

• SKU: MEXHY-P991240-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-P991240-0
• Package Unit: Get quote
• Quantity Unit: STK
• Conjugate: Unconjugated