CeMMEC1, CAS 440662-09-9

Shelf life (days): 1460.0

Formulation: A crystalline solid

Formal Name: N-(2,3-dihydro-1,4-benzodioxin-6-yl)-1,2-dihydro-2-methyl-1-oxo-4-isoquinolinecarboxamide

Purity: ≥98%

Formula Markup: C19H16N2O4

Formula Weight: 336.3

CAS Number: 440662-09-9

Notes: CeMMEC1 is an N-methylisoquinolinone that inhibits the second bromodomain of TAF1 (Kd = 1.8 µM; IC50 = 0.9 µM).{31547} It does not bind to either the first or second bromodomain of BRD4.{31547} This compound synergizes with (+)-JQ1 (Item No. 11187) to inhibit the proliferation of THP-1 and H23 lung adenocarcinoma cells.{31547}

• SKU: CAY19956-5
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 19956-5
• Package Unit: 5 mg
• Quantity Unit: STK