Cerebral Dopamine Neurotrophic Factor, human recombinant (rHuCDNF)

Kategorie: Cytokines

Formulation: lyophilized

Storage: -20°C

Weight: 18500 D

Purity: >96%

Description: Human recombinant CDNF produced in E.coli is a single, non-glycosylated polypeptide chain containing 161 amino acids and having a molecular mass of 18.5kDa. CDNF is a member of the ARMET family and acts as a trophic factor for dopamine neurons. CDNF inhibits the 6-hydroxydopamine (6-OHDA)-induced degeneration of dopaminergic neurons. When CDNF controlled after 6-OHDA-lesioning, it reestablishes the dopaminergic function and inhibits the degeneration of dopaminergic neurons in substantia nigra. CDNF is universally expressed in neuronal and non-neuronal tissues. The highest levels in the brain are found in the optic nerve and corpus callosum.

• SKU: BOL97428.5
• Manufacturer: Biomol
• Manufacturer SKU: 97428.5
• Package Unit: 5 µg
• Quantity Unit: STK
• Reactivity: Human
• Human Gene ID: 441549
• Host: Escherichia Coli