Cevipabulin, CAS 849550-05-6

Product Description: Cevipabulin (TTI-237) is an oral, microtubule-active antitumor compound and inhibits the binding of [3H] vinblastine to tubulin, with an IC50 of 18-40 nM for cytotoxicity in human tumor cell line[1][2].

Applications: Cancer-programmed cell death

Formula: C18H18ClF5N6O

References: [1]Beyer CF, et al. TTI-237: a novel microtubule-active compound with in vivo antitumor activity. Cancer Res. 2008 Apr 1;68(7):2292-300./[2]Beyer CF, et al. The microtubule-active antitumor compound TTI-237 has both paclitaxel-like and vincristine-like properties. Cancer Chemother Pharmacol. 2009 Sep;64(4):681-9.

CAS Number: 849550-05-6

Molecular Weight: 464.82

Compound Purity: 99.86

Research Area: Cancer

Solubility: DMSO : 16.67 mg/mL (ultrasonic)

Target: Microtubule/Tubulin

• SKU: MEXHY-14949-10.1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-14949-10.1
• Package Unit: 10 mM/1 ml
• Quantity Unit: STK