Product Description: CGI-1746 is a potent and highly selective inhibitor of the?Btk?with?IC50?of 1.9 nM.
Applications: COVID-19-immunoregulation
Formula: C34H37N5O4
References: [1]Di Paolo, Julie A. et al. Specific Btk inhibition suppresses B cell- and myeloid cell-mediated arthritis. Nature Chemical Biology (2011), 7(1), 41-50/[2]Kokabee L, et al. Bruton's tyrosine kinase is a potential therapeutic target in prostate cancer. Cancer Biol Ther. 2015;16(11):1604-15
CAS Number: 910232-84-7
Molecular Weight: 579.69
Compound Purity: 99.39
Research Area: Inflammation/Immunology
Solubility: DMSO : ≥ 50 mg/mL
Target: Autophagy;Btk