Product Description: CGP52432 is a GABAB receptor antagonist, with an IC50 of 85 nM.
Applications: Neuroscience-Neuromodulation
Formula: C15H24Cl2NO4P
References: [1]Lanza M, et al. CGP 52432: a novel potent and selective GABAB autoreceptor antagonist in rat cerebral cortex. Eur J Pharmacol. 1993 Jun 24;237(2-3):191-5./[2]Sweeney FF, et al. Activation but not blockade of GABAB receptors during early-life alters anxiety in adulthood in BALB/c mice. Neuropharmacology. 2014 Jun;81:303-10./[3]Kobuchi S, et al. Mechanisms underlying the renoprotective effect of GABA against ischaemia/reperfusion-induced renal injury in rats. Clin Exp Pharmacol Physiol. 2015 Mar;42(3):278-86.
CAS Number: 139667-74-6
Molecular Weight: 384.24
Compound Purity: 98.16
Research Area: Neurological Disease
Solubility: DMSO : 5 mg/mL (ultrasonic;warming)/H2O : 4 mg/mL (ultrasonic;warming;heat to 60°C)
Target: GABA Receptor
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