Product Description: CGP71683 hydrochloride is a competitive neuropeptide Y5 receptor antagonist with a Ki of 1.3 nM, and shows no obvious activity at Y1 receptor (Ki, >4000 nM) and Y2 receptor (Ki, 200 nM) in cell membranes.
Applications: Neuroscience-Neuromodulation
Formula: C26H30ClN5O2S
References: [1]Lecklin A, et al. Receptor subtypes Y1 and Y5 mediate neuropeptide Y induced feeding in the guinea-pig. Br J Pharmacol. 2002 Apr;135(8):2029-37./[2]Costa-e-Sousa RH, et al. Central NPY-Y5 receptors activation plays a major role in fasting-induced pituitary-thyroid axis suppression in adult rat. Regul Pept. 2011 Nov 10;171(1-3):43-7.
CAS Number: 192322-50-2
Molecular Weight: 512.07
Compound Purity: 99.90
Research Area: Neurological Disease; Endocrinology
Solubility: DMSO : 160 mg/mL (ultrasonic)
Target: Neuropeptide Y Receptor
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