Chk2 Inhibitor II, CAS 516480-79-8

Shelf life (days): 1460.0

Formulation: A crystalline solid

Formal Name: 2-[4-(4-chlorophenoxy)phenyl]-1H-benzimidazole-6-carboxamide

Purity: ≥98%

Formula Markup: C20H14ClN3O2

Formula Weight: 363.8

CAS Number: 516480-79-8

Notes: Chk2 inhibitor II is a selective, ATP-competitive inhibitor of the DNA damage control kinase, checkpoint kinase 2 (IC50 = 15 nM).{28503} It has been shown to prevent apoptosis in human T-cells exposed to ionizing radiation (EC50 = 3-7.6 µM).{28503} This compound has been used to target the role of Chk2 in cellular signaling in response to DNA damage.{28504}

• SKU: CAY17552-5
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 17552-5
• Package Unit: 5 mg
• Quantity Unit: STK