Shelf life (days): 1460.0
Formulation: A crystalline solid
Formal Name: 5-chloro-2(3H)-benzoxazolone
Purity: ≥98%
Formula Markup: C7H4ClNO2
Formula Weight: 169.6
CAS Number: 95-25-0
Notes: Chlorzoxazone is a centrally acting muscle relaxant and activator of small and intermediate conductance calcium-activated potassium channels (EC50s = 87 and 98 µM for KCa2.2 and KCa3.1, respectively).{27789,23031} In vivo, chlorzoxazone (10 mg/kg) decreases alcohol but not water intake in a dose-dependent manner and reduces the propensity for rapid initial alcohol intake in rats with intermittent, but not continuous, access to alcohol.{43334} Formulations containing chlorzoxazone have been used in the treatment of pain and stiffness caused by muscle spasm. This product is also available as an analytical reference standard (Item No. 25826).
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