Chroman 1, CAS 1273579-40-0

Product Description: Chroman 1 is a highly potent and selective ROCK inhibitor. Chroman 1 is more potent against ROCK2 (IC50=1 pM) than ROCK1 (IC50=52 pM). Chroman 1 also has inhibitory activity against MRCK, with an IC50 of 150 nM[1][2].

Applications: COVID-19-anti-virus

Formula: C24H28N4O4

References: [1]Yen Ting Chen, et al. Asymmetric synthesis of potent chroman-based Rho kinase (ROCK-II) inhibitors. Med.Chem.Commun., 2011, 2, 73-75./[2]Yu Chen, et al. A Versatile Polypharmacology Platform Promotes Cytoprotection and Viability of Human Pluripotent and Differentiated Cells. bioRxiv 815761.

CAS Number: 1273579-40-0

Molecular Weight: 436.50

Compound Purity: 99.42

Research Area: Cardiovascular Disease

Solubility: DMSO : ≥ 50 mg/mL

Target: ROCK

• SKU: MEXHY-15392-10.1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-15392-10.1
• Package Unit: 10 mM/1 ml
• Quantity Unit: STK