Cinacalcet (hydrochloride), CAS 364782-34-3

Shelf life (days): 730.0

Formulation: A crystalline solid

Formal Name: aR-methyl-N-[3-[3-(trifluoromethyl)phenyl]propyl]-1-naphthalenemethanamine, monohydrochloride

Purity: ≥95%

Formula Markup: C22H22F3N / HCl

Formula Weight: 393.9

CAS Number: 364782-34-3

Notes: Cinacalcet is a calcimimetic and an allosteric agonist of the calcium-sensing receptor (CaSR; EC50 = 79.4 nM in HEK293T cells expressing the human receptor).{26279} In vivo, cinacalcet (0.1-10 mg/kg, s.c.) decreases plasma levels of parathyroid hormone (PTH) in rats. It also decreases plasma levels of PTH and parathyroid cell proliferation in a mouse model of primary hyperparathyroidism.{39827} Formulations containing cinacalcet have been used in the treatment of secondary hyperparathyroidism due to end-stage renal disease and hypercalcemia in patients with parathyroid carcinoma.

• SKU: CAY16042-50
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 16042-50
• Package Unit: 50 mg
• Quantity Unit: STK