cis-SU4312, CAS 90828-16-3

Product Description: cis-SU4312 ((Z)-SU4312) inhibits PDGFR and FLK-1 with IC50s of 19.4 and 0.8 μM, respectively. cis-SU4312 inhibits PDGFR, FLK-1, EGFR, HER-2, and IGF-1R with IC50s of 24.2, 5.2, 18.5, 16.9 and 10.0 μM, respectively. cis-SU4312 can cross blood brain barrier[1].

Applications: Cancer-Kinase/protease

Formula: C17H16N2O

References: [1]Wei Cui, et al. The anti-cancer agent SU4312 unexpectedly protects against MPP(+) -induced neurotoxicity via selective and direct inhibition of neuronal NOS. Br J Pharmacol. 2013 Mar;168(5):1201-14.

CAS Number: 90828-16-3

Molecular Weight: 264.32

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: PDGFR;VEGFR

• SKU: MEXHY-100349A-5
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-100349A-5
• Package Unit: 5 mg
• Quantity Unit: STK