cis VH-298, CAS 2097381-86-5

Product Description: cis VH-298 is the cis form of VH-298 (HY-100947). cis VH-298 results in a significant loss of binding specificity of hydroxylated HIF-1a peptides to VHL in vitro[1].

Applications: Cancer-programmed cell death

Formula: C27H33N5O4S

References: [1]Frost J, et al. Potent and selective chemical probe of hypoxic signalling downstream of HIF-α hydroxylation via VHL inhibition. Nat Commun. 2016 Nov 4;7:13312.

CAS Number: 2097381-86-5

Molecular Weight: 523.65

Research Area: Cancer; Inflammation/Immunology; Others

Solubility: 10 mM in DMSO

Target: HIF/HIF Prolyl-Hydroxylase;Ligands for E3 Ligase

• SKU: MEXHY-100947A-10
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-100947A-10
• Package Unit: 10 mg
• Quantity Unit: STK