Shelf life (days): 1460.0
Formulation: A solid
Formal Name: N-(2-aminoethyl)-5-chloro-8-isoquinolinesulfonamide, dihydrochloride
Purity: ≥98%
Formula Markup: C11H12ClN3O2S / 2HCl
Formula Weight: 358.67198
CAS Number: 1177141-67-1
Notes: CKI-7 is an inhibitor of casein kinase 1 (CK1; Ki = 8.5 μM).{47508} It is selective for CK1 over CK2, PKC, CaM kinase II (CaMKII), and cyclic AMP-dependent protein kinase (IC50s = 90, >1,000, 195, and 550 μM, respectively). CKI-7 inhibits phosphorylation of a peptide substrate by Leishmania CK1.2 by 50% when used at a concentration of 10 μM.{28924}