Cl-Amidine (hydrochloride), CAS 1373232-26-8

Shelf life (days): 1460.0

Formulation: A crystalline solid

Formal Name: N-[(1S)-1-(aminocarbonyl)-4-[(2-chloro-1-iminoethyl)amino]butyl]-benzamide, monohydrochloride

Purity: ≥95%

Formula Markup: C14H19ClN4O2 / HCl

Formula Weight: 347.23976

CAS Number: 1373232-26-8

Notes: A PAD inhibitor (IC50s = 0.8, 6.2, and 5.9 µM for PAD1, PAD3, and PAD4, respectively); cytotoxic to HL-60, MCF-7, and HT-29 cancer cells (IC50s = 0.25, 0.05, and 1 μM, respectively); reduces ex vivo extracellular NET formation and increases survival in a mouse model of CLP-induced sepsis at 50 mg/kg; decreases the citrulline content in serum and joints and reduces the development of IgG autoantibodies in a mouse model of collagen-induced arthritis

• SKU: CAY10599-25
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 10599-25
• Package Unit: 25 mg
• Quantity Unit: STK