Clozapine (hydrochloride), CAS 2711603-38-0

Shelf life (days): 1460.0

Formulation: A crystalline solid

Formal Name: 8-chloro-11-(4-methyl-1-piperazinyl)-5H-dibenzo[b,e][1,4]diazepine, dihydrochloride

Purity: ≥98%

Formula Markup: C18H19ClN4 / 2HCl

Formula Weight: 399.7444

CAS Number: 2711603-38-0

Notes: An atypical antipsychotic; a partial agonist of the 5-HT1A receptor (Ki = 180 nM); binds to the 5-HT2A, 5-HT2C, 5-HT3, 5-HT6, and 5-HT7 receptors (Kis = 3.3, 13, 110, 4, and 21 nM, respectively); binds to histamine H1 and α1-adrenergic receptors (Kis = 2.1 and 23 nM, respectively); induces the release of glutamate and D-serine from astrocytes; reverses locomotor hyperactivity and deficits in prepulse inhibition of acoustic startle in a rat neonatal ventral hippocampal ibotenic lesion model of schizophrenia at 2.5 mg/kg per day

• SKU: CAY25779-50
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 25779-50
• Package Unit: 50 mg
• Quantity Unit: STK