CLP 290, CAS 1181083-81-7

Shelf life (days): 1460.0

Formulation: A crystalline solid

Formal Name: 1-pyrrolidinecarboxylic acid, 5-fluoro-2-[(Z)-[4-oxo-2-(tetrahydro-1(2H)-pyridazinyl)-5(4H)-thiazolylidene]methyl]phenyl ester

Purity: ≥98%

Formula Markup: C19H21FN4O3S

Formula Weight: 404.459603

CAS Number: 1181083-81-7

Notes: CLP 290 is a carbamate prodrug form of the K+/Cl- cotransporter 2 (KCC2) activator CLP 257 (Item No. 30948).{57069} It increases the mechanical paw withdrawal threshold in a rat model of peripheral nerve injury and reverses morphine-induced hyperalgesia in rats when administered at a dose of 100 mg/kg.{57069,57072} CLP 290 (35 mg/kg) also restores stepping ability, as well as increases body weight support and stride length, in a mouse model of paralysis induced by staggered spinal lesions.{57226}

• SKU: CAY31448-1
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 31448-1
• Package Unit: 1 mg
• Quantity Unit: STK