Target Synonym: CK;UMP-CMPK;CMK;CMPK;UCK;UMK;UMPK;CMPK1;CMPK 1;Cytidine monophosphate (UMP CMP) kinase 1 cytosolic;Cytidine monophosphate kinase;Cytidine monophosphate UMP CMP kinase 1 cytosolic;Cytidylate kinase;dCMP kinase;Deoxycytidylate kinase;EC 2.7.4.14;KCY;Monophosphatase kinase;OTTHUMP00000009565;RP11 511I2.1;UMP CMP;UMP CMP kinase;UMP/CMP kinase;UMP/CMPK;UMP-CMP kinase;Uridine monophosphate kinase;Uridine monophosphate/cytidine monophosphate kinase
Background: CMPK1 plays a key role in the maintenance of pyrimidine nucleotide pool profile and for the metabolism of pyrimidine analogs in cells. It catalyzes the phosphoryl transfer from ATP to UMP, CMP, and deoxy-CMP (dCMP), resulting in the formation of ADP and the corresponding nucleoside diphosphate. CMPK1 also has a significant role in the activation of pyrimidine analogs, which are clinically useful anti-cancer and anti-viral drugs. In the meanwhile, CMPK1 functions in cellular nucleic acid biosynthesis.
Immunogen: Recombinant Human CMPK1 Protein
Buffer: 0.2 μm filtered solution in PBS
Dilution: WB 1:500-1:2000;
Calculated MW: 22 kDa
Observed MW: 22 kDa
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