Product Description: Compound 401 is a synthetic inhibitor of DNA-PK (IC50 = 0.28 μM) that also targets mTOR but not PI3K in vitro.
Applications: Cancer-Kinase/protease
Formula: C16H15N3O2
References: [1]Ballou LM, et al. Inhibition of mammalian target of rapamycin signaling by 2-(morpholin-1-yl)pyrimido[2,1-alpha]isoquinolin-4-one. J Biol Chem. 2007 Aug 17;282(33):24463-70.
CAS Number: 168425-64-7
Molecular Weight: 281.31
Compound Purity: 99.09
Research Area: Cancer
Solubility: DMSO : 10 mg/mL (ultrasonic;warming;heat to 80°C)