Microbiology

We offer a wide range of products for the detection of infections caused by bacteria, viruses, fungi, protozoa and parasites. The methods range from nucleic acid amplification tests, ELISAs and rapid tests to indirect and direct immunofluorescence for various sample materials. The subgroups are divided according to method / technology.

The latest "highlights" are molecular tests that do not require a separate clean room (PCR room). Here we offer the following products from Meridian Bioscience:

ALETHIA® MOLECULAR TESTS

  • Alethia® C. difficile
    DNA amplification test for the detection of toxigenic C.difficile in stool samples.
  • Alethia® CMV
    DNA amplification assay for the direct detection of cytomegalovirus (CMV) DNA in saliva samples from newborns younger than 21 days.
  • Alethia®Group B Streptococcus
    DNA amplification test for the detection of Group B Streptococcus (GBS) in vaginal / rectal antepartum smears.
  • Alethia®Group A Streptococcus
    DNA amplification test for the detection of Streptococcus pyogenes (Group-A ß-hemolytic Streptococcus) in throat swabs.
  • Alethia® Mycoplasma Direct
    DNA amplification test for the detection of Streptococcus pyogenes (Group-A ß-hemolytic Streptococcus) in throat swabs.
  • Alethia® Pertussis
    DNA amplification test for the detection of Bordetella pertussis in nasopharyngeal smears.
  • Alethia® Chlamydia (CT)
    DNA amplification test for the detection of Chlamydia trachomatis in endocervical swabs, self-taken vaginal swabs and urine samples (female / male).
  • Alethia®Gonorrhea (NG)
    DNA amplification test for the detection of Neisseria gonorrhoeae in endocervical swabs, self-taken vaginal swabs and urine samples (female / male).
  • Alethia® HSV 1&2 Assay
    DNA amplification test for the detection of Herpes Simplex Virus Type 1 and Type 2 in cutaneous and mucocutaneous lesions.
  • Alethia®Malaria
    DNA amplification test for the detection of Plasmodium spp. in human whole blood.
  • Alethia® Malaria Plus
    DNA amplification test for the detection of Plasmodium spp. in human whole blood.

REVOGENE® MOLECULAR (PCR) TESTS

  • REVOGENE® Strep A Test Kit
    The Revogene® Strep A test is a direct qualitative in vitro PCR diagnostic test for the detection of the DNA of Streptococcus pyogenes (Group A β-hemolytic streptococcus; GAS) in throat swabs in patients with signs and symptoms of pharyngitis.
  • REVOGENE® C.diff. Test Kit
    The Revogene® C. difficile test is a simple and direct qualitative in vitro PCR diagnostic test for the detection of the toxin B (tcdB) gene of C. difficile in liquid or loose stool samples from patients with suspected C. difficile infection (CDI).
  • REVOGENE® Carb C Test Kit
    The Revogene Carba® C test is a simple and direct qualitative in vitro PCR diagnostic test for the detection and differentiation of the gene sequences blaKPC, blaNDM, blaVIM, blaOXA-48-like and blaIMP associated with carbapenem-resistant pure colonies of Enterobacteriaceae, Acinetobacter baumannii or Pseudomonas aeruginosa if you grow up on blood agar or MacConkey agar.
  • REVOGENE® GBS DS Test Kit
    The Revogene® GBS DS test is a qualitative in vitro PCR diagnostic test for the detection of the DNA of group B streptococci (GBS) and ensures accurate results and the timely administration of appropriate antibiotics to GBS-positive patients.

 

OVERVIEW

 

BACTERIA ELISA

Our product range includes both serological antibody and direct antigen determinations.

Serological or direct antigen determinations of infectious diseases are a non-invasive alternative and have many advantages, such as:

  • Easy sample collection
  • Easy handling thanks to standardized protocols
  • Appropriate follow-up examination
  • Identification of persistent infections
  • High positive prognostic value for persistent infections
  • High positive or negative predictive values

 

Together with our partner companies, we offer you high-quality, user-friendly ELISAs for the following parameters:

A-PATHOGENIC RESPIRATORY INFECTIONS

BORDETELLA PERTUSSIS

INTRODUCTION:

Whooping cough (pertussis) is a highly contagious bacterial respiratory tract infection caused by Bordetella pertussis - Gram-negative bacilli. Pertussis usually occurs in children with paroxysmal convulsions with a severe cough. Coughing and post-tussive vomiting last for several weeks.

The disease leads to high morbidity and mortality, especially in children.

 

SEROPERTUSSIS™

The SeroPertussis™ product line from Savyon Dagnostics uses the purified Bordetella pertussis extract, enriched with PT (pertussis toxin) and FHA (filamentous hemagglutinin) as antigen for the detection of specific antibodies against Bordetella pertussis in human serum.

SeroPertussis™ IgG is a semi-quantitative assay with 3 ready-to-use calibrators - P10, P50, P100 - to calculate the standard curve, from which the O.D. (optical density) is evaluated as BU / ml.

SeroPertussis IgA / IgM is a qualitative assay for the flexible detection of IgA and / or IgM antibodies.

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SEROPERTUSSIS™ TOXIN

The new SeroPertussis™ Toxin ELISAs from Savyon Diagnostics are quantitative detection kits for IgG and IgA antibodies against the pertussis toxin. The results are reported in international units / ml (IU / ml). The kits were designed according to the recently issued recommendations of the EU Reference Laboratories, the WHO standard calibrators were used for standardized quantification. (1.2)

In the SeroPertussis™ Toxin Tests, purified pertussis toxin is used as the antigen. These are specific to B. pertussis antibodies and do not cross-react with B. parapertussis.

Biography:

1. N. Guiso, G. Berbers, N. K. Fry, Q. He , M. Riffelmann, C. H. Wirsing von König, EU Pertstrain group (2011)
What to do and what not to do in serological diagnosis of pertussis: recommendations from EU reference
laboratories. Eur J Clin Microbiol Infect Dis 30:307–312.
2. M. Riffelmann, K. Thiel, J. Schmetz and C. H. Wirsing von Koenig (2010). Performance of Commercial
Enzyme-Linked Immunosorbent Assays for Detection of Antibodies to Bordetella pertussis. J. Clin. Micro.
48(12); 4459-4463
3. Khalid Katfy1,2*, Idrissa Diawara1,2,6, Fakhredine Maaloum1,2, Siham Aziz2, Nicole Guiso5, Hassan Fellah3,
Bouchra Slaoui4, Khalid Zerouali1,2, Houria Belabbes1,2 and Naima Elmdaghri1,2 Pertussis in infants, in their
mothers and other contacts in Casablanca, Morocco. BMC Infectious Diseases (2020) 20:43; 2-9.

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CHLAMYDOPHILA PNEUMONIAE AND MYCOPLASMA PNEUMONIAE

The most common A-pathogenic agents associated with respiratory infections (RTI) and “community acquired pneumonia” (CAP) are Chlamydophila pneumoniae and Mycoplasma pneumoniae. Both pathogens are widespread and cause severe pneumonia infections in children and adolescents.Savyon Diagnostics offers very sensitive and species-specific ELISAs for the determination of antibodies against Chlamydophila pneumoniae and Mycoplasma pneumoniae.

 

SEROCP™

SeroCP ™ Quant is a second generation test for the semi-quantitative identification of Chlamydophila pneumoniae IgG and IgA antibodies. The test uses 3 calibrators - P10, P50, P100 - included in the kit to generate a standard curve. The sample OD's (optical density) are evaluated using a standard curve in BU / ml units. The test protocol makes it possible to calculate the kinetics of the IgG and IgA antibodies in the paired sera in order to better diagnose the status of the infection.

For the complete range of Savyon Diagnostics products, please visit our webshop.

 

SEROMP™

SeroMP ™ is a solid phase ELISA kit for the semi-quantitative identification of Mycoplasma pneumoniae IgM, IgA and IgG antibodies based on a native antigen. An overall antibody profile enables improved diagnostics and therapy.

For the complete range of Savyon Diagnostics products, please visit our webshop.

 

SEROMP™ RECOMBINANT

SeroMP ™ Recombinant Kits are the new semi-quantitative ELISA kits for the identification of Mycoplasma penumoniae IgG and IgA antibodies based on a recombinant antigen and IgM based on a combination of native and recombinant antigen. With the use of recombinant antigens, increased specificity for Mycoplasma pneumoniae is achieved without losing sensitivity. Borderline results are significantly reduced, making it easier to differentiate between healthy and diseased populations.

For the complete range of Savyon Diagnostics products, please visit our webshop.

 

CHLAMYDIA

Chlamydia trachomatis is a very common bacterium that causes sexually transmitted infections. If these infections are not diagnosed or treated, they can lead to serious chronic inflammation with serious complications.

Savyon Diagnostics offers very sensitive and species-specific ELISA kits for the determination of antibodies against Chlamydia trachomatis:

 

SEROCT™

SeroCT™ is the first ELISA test - for the detection of C. trachomatis antibodies - based on C. trachomatis species-specific peptides as antigens. The peptides in the kits originate from Chlamydia species-specific immunodominant proteins. These proteins share sequences with all C. trachomatis serogroups and have no homology with other Chlamydia species.

SeroCT™ offers high sensitivity and specificity in the identification of IgG and IgA anti-Chlamydia antibodies and enables a complete diagnosis of acute, past and chronic infections. No cross-reactions were observed specifically with C. pneumoniae.

SeroCT™ Assay results are calculated as Cut Off Index (COI) values ​​that allow comparison between results. A conversion table can be used to semiquantify the results as end-point titer from the cut-off index.

For the complete range of Savyon Diagnostics products, please visit our webshop.

MERIDIAN BIOSCIENCE

Meridian Bioscience Europe Logo

The Meridian product range is very extensive based on various technologies, such as nucleic acid amplification (Alethia®), ELISA (Premier®), rapid tests (ImmunoCard® or TRU® format), indirect immunofluorescence tests = IIFT (MERIFLUOR®), direct fluorescence tests = DFT, immunodiffusion and stool transport (Para-Pak®).

These high quality products are used for diagnostics in the following areas:

  • Bacteriology
  • Respiratory infections
  • Food infections
  • Viral gastroenteritis
  • Parasitic Infections
  • Virology
  • Mononucleosis
  • Fungal infections

For the complete range of Meridian Bioscience products, please visit our webshop.
We will be happy to send you the new Meridian Bioscience product catalog on request.

 

STOOL PATHOGENIC BACTERIA ELISAS

CLOSTRIDIUM DIFFICILE

Premier® C. difficile GDH ELISA for the detection of C. difficile Common Antigen directly from stool samples.

This ELISA delivers extremely accurate results quickly, efficiently and inexpensively. Negative results can be excluded in the early phase. The negative predictive value (NPV) is at> 97%, the sensitivity at 94% and the specificity at 95%.

The ease of use and flexibility make work in the laboratory easier. The quick (<1 hour) work log speaks for itself. The evaluation can be done either visually or using a photometer.

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Premier® Toxin A&B Elisa for the detection of C. difficile toxins A and B directly from stool samples.

This traditional toxin A&B Elisa that has been around for a long time provides the results you want with simple steps.

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HELICOBACTER PYLORI

Premier® Platinum HpSA PLUS for the detection of H. pylori in stool samples.

This ELISA is a qualitative in vitro test for the detection of Helicobacter pylori antigens in human stool samples. The results serve as an aid for the diagnosis of H. pylori infections and for monitoring the patient's response during and after therapy. In order to ensure the success of the therapy and its eradication, it is recommended in current medical practice to carry out a test no earlier than 4 weeks after the end of therapy.

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EHEC/ENTEROHAEMORRHAGIC E. COLI

Premier® EHEC ELISA for the detection of toxins produced by E. coli in human stool samples and cultures.

This ELISA is a fast in vitro test for the detection of Shiga toxins I and II in human stool samples, liquid cultures, individual colonies or colonies smears on agar plates. Premier EHEC is used as an aid in the diagnosis of enterohaemorrhagic E. coli (EHEC) infections.

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CAMPYLOBACTER

Premier® CAMPY for the detection of campylobacteria antigens in stool samples.

This ELISA is a qualitative in vitro test for the detection of specific Campylobacter antigens in stool samples in patients with suspected gastroenteritis. Premier® CAMPY detects C. jejuni and C. coli in human stool samples that are either native or preserved in Cary-Blair medium. The results should be used in conjunction with the clinical picture and / or other diagnostic tests.

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STOOL PATHOGENIC BACTERIA RAPID TESTS

CLOSTRIDIUM DIFFICILE

According to the guidelines of the European Society of Clinical Microbiology and Infectious Diseases (ESMID), American Society for Microbiology (ASM) and Infectious Diseases Society of America (IDSA) together with the Society for Healthcare and Epidemiology of America (SHEA), Clostridium difficile diagnostics recommended as a one- or two-step algorithm.

A molecular test can be used as the sole method.

SZABO-SCANDIC offers the molecular Alethia® Clostridium difficile or the real-time PCR RIDA® GENE Clostridium difficile test.

You can find more information in the Molecular Diagnostics section under LAMP technology and Real-Time PCR.

 

Example two-stage algorithm:

  1. Clostridium difficile GDH (glutamate dehydrogenase) determination (ELISA or rapid test).
  2. The resulting positive samples are recommended using the molecular Clostridium difficile test Alethia®.

 

ImmunoCard®C. difficile GDH (glutamate dehydrogenase) rapid test is an enzyme immunoassay for the detection of C. difficile general antigen, glutamate dehydrogenase.

With an excellent sensitivity of 97.6% and a very high NPV = negative predictive value of 99.6% (confirmed in clinical studies), this test enables rapid and reliable screening of patient samples if C. difficile infection (CDI) is suspected.

The simple handling with just a few hand movements gives reliable and easy to interpret results in less than 30 minutes.

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ImmunoCard®C. difficile GDH-AB rapid test

The Immunocard STAT! C. difficile GDH-AB test is a qualitative, immunochromatographic rapid test for the simultaneous detection of the antigen glutamate dehydrogenase of Clostridium difficile (GDH, is produced by toxigenic and non-toxigenic strains) as well as the toxins A and B produced by Clostridium difficile.

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Meridian Bioscience has further rapid tests for diagnosing stool pathogens:

ENTEROHAEMORRHAGIC ESCHERICHIA COLI/EHEC

ImmunoCard  STAT!® EHEC is a rapid enzyme immunoassay for the detection of E. coli Shigatoxin 1 and 2 directly from human stool samples.

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ImmunoCard  STAT!® E. coli O157 Plus is a rapid enzyme immunoassay for the detection of Shiga toxin-producing E. coli O157 in human stool samples and in cultures.

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CAMPYLOBACTER

ImmunoCard® STAT! CAMPY is a rapid enzyme immunoassay for the detection of specific Campylobacter antigens in human stool samples.

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STOOL PATHOGENIC RT PCR KITS

RIDA®GENE Bacterial Stool Panel is a real-time multipex PCR for the direct qualitative detection and differentiation of human pathogenic Salmonella spp., Campylobacter spp. and Yersinia enterocolitica in human stool samples. The RIDA®GENE Bacterial Stool Panel real-time multiplex PCR is designed to support the diagnosis of gastrointestinal infection caused by bacteria.

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RIDA®GENE Bacterial Stool Panel I is a multiplex real-time PCR for the direct qualitative detection and differentiation of STEC, Salmonella spp., EIEC/Shigella spp. and Campylobacter spp. from human stool samples.

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RIDA®GENE EHEC/EPEC is a real-time multiplex PCR for the direct qualitative detection and differentiation of the pathogenicity factor genes of EHEC, STEC, EPEC and EIEC/Shigella spp. in human stool and culture samples. The RIDA®GENE EHEC/EPEC real-time multiplex PCR is intended to support the diagnosis of gastroenteritis caused by pathogenic Escherichia coli or Shigella spp.

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RIDA®GENE EAEC is a real-time multiplex PCR for the direct qualitative detection of enteroaggregative E. coli (EAEC) in human stool and culture samples. The RIDA®GENE EAEC real-time multiplex PCR is intended to support the diagnosis of gastroenteritis caused by enteroaggregative E. coli.

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RIDA®GENE ETEC/EIEC is a multiplex real-time PCR for the direct qualitative detection and differentiation of the pathogenicity factor genes of ETEC and EIEC/Shigella spp. in human stool and culture samples. The RIDA®GENE ETEC/EIEC multiplex real-time PCR is intended to support the diagnosis of gastroenteritis caused by pathogenic Escherichia coli or Shigella spp.

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RIDA®GENE E. coli Stool Panel I is a multiplex real-time PCR for direct qualitative detection and differentiation of genes for the virulence factors of EPEC and STEC (stx 1, stx 2 and eae) in human stool samples. The RIDA®GENE E. coli Stool Panel I multiplex real-time PCR is intended to support the diagnosis of gastroenteritis caused by EPEC or STEC.

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RIDA®GENE Helicobacter pylori is a real-time PCR for the direct qualitative detection of Helicobacter pylori and clarithromycin resistance from human native biopsy material. The RIDA®GENE Helicobacter pylori real-time PCR is intended to support the diagnosis of a stomach disease caused by Helicobacter pylori.

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RIDA®GENE Hospital Stool Panel is a real-time multiplex RT-PCR for the direct qualitative detection and differentiation of norovirus (genogroup I and II), rotavirus and the Clostridium difficile toxin genes A (tcdA) and B (tcdB) in human stool samples. The RIDA®GENE Hospital Stool Panel real-time multiplex RT-PCR is designed to support the diagnosis of hospital-acquired gastroenteritis.

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RIDA®GENE Clostridium difficile is a real-time multiplex PCR for the direct qualitative detection of Clostridium difficile (16S-rDNA) and clostridium difficile toxin genes A (tcdA) and B (tcdB) from human stool and culture samples. The RIDA®GENE Clostridium difficile real-time multiplex PCR is intended to support the diagnosis of Clostridium difficile associated diarrhea (CDAD).

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RESPIRATORY INFECTIONS

Alethia® Group A Streptococcus

Background:

Streptococcus pyogenes is a beta-hemolytic gram-positive cocci that has about 80 serogroups, of which M1 and M3 are the most common. A non-invasive GAS causes tonsillitis (pharyngitis) or skin infections (impetigo, erysipelas, phlegmon).

A prophage β virus infected streptococcal bacterium can produce pyrogenic streptococcal exotoxin (PSE). This occurs in serotypes A, B, C and F and is responsible e.g. for the following diseases: scarlet fever, streptococcal-induced toxic shock syndrome (STSS), necrotizing fasciitis. Serious immunological sequelae such as rheumatoid fiber, reactive arthritis and glomerulonephritis can develop.

Transmission is transmitted from person to person through contact with the nasal or throat mucus or wound.

 

Diagnosis:

The following methods are used in laboratory diagnostics to detect GAS. Traditional culture method that shows a fairly high (around 10%) false negative rate. It needs a confirmation test to precisely identify the germ. There are also direct antigen rapid tests with sensitivities of 80-90% and highly sensitive nucleic acid amplification determinations.

 

Meridian offers the Alethia® Group A Streptococcus Molecular Test, which is the only FDA-cleared molecular amplification test for Group A Streptococcus in throat swabs. The target is a conserved 206 base pair sequence in the S. pyogenes pyrogenic exotoxin B (speB) region.

With a high sensitivity of 98% and specificity of 97.7%, this test gives the following advantages:

  • The only clinically defined molecular amplification test for Group A Streptococcus.
  • 53% more positive samples are detected compared to traditional culture.
  • More accurate results than the rapid tests or culture.
  • Quick (<1h) and easy to implement.

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TEST PROCEDURE

For the PDF document click on the picture.

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TRU Legionella®high quality urine antigen rapid test.

A lateral flow immunoassay for the qualitative detection of Legionella pneumophila serogroup 1 antigen in human urine samples. The test is intended for patients who have symptoms of pneumonia. With three simple steps and in just 20 minutes, accurate, easy-to-read results are obtained in a closed system. Using the external controls supplied (positive and negative), a quality control = QC of the tests - in addition to the internal control included in the test strip - can be carried out.

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TEST PROCEDURE

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FURTHER PARAMETERS / RESPIRATORY INFECTIONS

ImmunoCard®

ImmunoCard® Mycoplasma IgM

A rapid enzyme immuno test for the detection of Mycoplasma pneumoniae IgM in human serum.

ImmunoCard® Mycoplasma IgM is a qualitative test (EIA) and is used to diagnose recent Mycoplasma pneumoniae infections.

 

Immunocard® STAT! Flu A&B

A rapid test for the detection of influenza A and B viral antigens in nasal lavage, nasal puncture, nasopharyngeal swab and nasal swab.

A rapid in vitro test for the qualitative nucleoprotein detection of influenza type A and type B antigens directly from nasal swabs, nasopharyngeal swabs, and nasopharyngeal aspirate / irrigation fluid samples from patients with signs and symptoms of a respiratory infection. The test serves as a tool for the rapid differential diagnosis of infections with the influenza A and B viruses.

 

TRU RSV®

TRU RSV®

A rapid test for the detection of Respiratory Syncytial Virus (RSV) antigens in nasal lavage, nasal puncture, nasopharyngeal swab and nasal swab.

This rapid, qualitative lateral flow immunochromatographic test is used to detect RSV antigens (binding protein or nucleoprotein) in symptomatic children (<5 years).

Legionella pneumophila

Serogroups 1-6, 1-8 and individually 1, 2, 3, 4, 5 and 6

Indirect immunofluorescence test kits for the detection of antibodies against the above mentioned serogroups. The components are also available individually.

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RESPIRATORY INFECTIONS RT PCR

RIDA®GENE Adenovirus is a real-time PCR for the direct qualitative detection of adenovirus from human throat irrigation water, sputum, and bronchoalveolar lavage (BAL). RIDA®GENE Adenovirus real-time PCR is designed to support the diagnosis of respiratory infection caused by adenovirus.

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RIDA®GENE Flu is a real-time multiplex RT-PCR for the direct qualitative detection and differentiation of influenza viruses (influenza A, influenza B and H1N1v) in human nasal and throat swabs. The RIDA®GENE Flu real-time multiplex RT-PCR is designed to support the diagnosis of respiratory infection caused by influenza viruses. Roche's LC 2.0 has its own kit!

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RIDA®GENE Flu & RSV is a multiplex real-time RT-PCR for the direct qualitative detection and differentiation of influenza viruses (influenza A, influenza B) and respiratory syncytial virus (RSV) from human nasal and throat swabs. The RIDA®GENE Flu & RSV multiplex real-time RT-PCR is designed to support the diagnosis of respiratory infection caused by influenza viruses and RSV.

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The RIDA®GENE Flu & SARS-CoV-2 test is a multiplex real-time RT-PCR for the direct qualitative detection and differentiation of Flu A/Flu B and coronavirus (SARS-CoV-2) RNA from human nasopharyngeal swabs of individuals with signs and symptoms of respiratory infection.

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The RIDA®GENE SARS-CoV-2 test, performed on the Roche LightCycler® 480II, is a multiplex real-time RT-PCR for the direct qualitative detection of coronavirus (SARS-CoV-2) RNA from human nasopharyngeal swab in people with signs and symptoms of respiratory infection.

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RIDA®GENE Parainfluenza is a multiplex real-time RT-PCR for the direct qualitative detection and differentiation of human parainfluenza viruses (parainfluenza 1, parainfluenza 3 and parainfluenza 2/4) from human nasal and pharyngeal swab. The RIDA®GENE Parainfluenza multiplex real-time RT-PCR is intended to support the diagnosis of respiratory infection caused by parainfluenza viruses.

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RIDA®GENE RSV & hMPV is a multiplex real-time RT-PCR for the direct qualitative detection and differentiation of respiratory synciial virus (A/B) and human metapneumovirus (1-4) from human nasopharyngeal swab, nasopharyngeal swab, throat irrigation fluid and BAL. The RIDA®GENE RSV & hMPV multiplex real-time RT-PCR is designed to support the diagnosis of respiratory infection caused by respiratory syncitic virus or human metapneumovirus.

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RIDA®GENE CAP Bac is a multiplex real-time PCR for the direct qualitative detection and differentiation of Chlamydophila pneumoniae (Chlamydia pneumoniae), Legionella pneumophila and Mycoplasma pneumoniae in human bronchoalveolar lavage (BAL).

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RIDA®GENE Bordetella is a real-time multiplex PCR for the direct qualitative detection and differentiation of Bordetella pertussis, Bordetella parapertussis and Bordetella holmesii from human nasopharyngeal smears and rinses. The RIDA®GENE Bordetella real-time multiplex PCR is intended to support the diagnosis of whooping cough caused by Bordetella pertussis, Bordetella parapertussis or Bordetella holmesii.

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RIDA®GENE Legionella is a real-time multiplex PCR for the direct qualitative detection and differentiation of Legionella pneumophila and Legionella spp. from human tracheal secretion, bronchoalveolar lavage and sputum. The RIDA®GENE Legionella real-time multiplex PCR is designed to support the diagnosis of pneumonia caused by Legionella.

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RIDA®GENE Pneumocystis jirovecii is a real-time PCR for the direct qualitative and quantitative detection of Pneumocystis jirovecii DNA from human bronchoalveolar lavage (BAL). RIDA®GENE Pneumocystis jirovecii real-time PCR is designed to support the diagnosis of respiratory infection caused by Pneumocystis jirovecii.

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RESPIRATORY INFECTIONS RT PCR (POC)

Revogeneic® Strep A Test is a direct qualitative in vitro PCR diagnostic test for the detection of the DNA of Streptococcus pyogenes (Group A β-hemolytic Streptococcus; GAS) in throat swabs in patients with signs and symptoms of pharyngitis.

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BAKTERIOLOGY IFT/IPT

Some pathogens can still be detected very well using indirect or direct immunofluorescence (IFT) or immunoperoxidase (IPT) tests. We offer an extensive range of products from our long-term partner company BIOS for the following parameters / bacteria (methods: IFT).

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All of these products are available as complete kits, including slides, conjugate, controls and buffer, or as individual components.

For the complete product range of BIOS GmbH visit our webshop.

 

CHLAMYDIA IFT AND IPT

The following tests are offered by Savyon Diagnostics using immunofluorescence / IFT and immunoperodixidase / IPT:

For the complete range of Savyon Diagnostics products, please visit our webshop.

 

VIROLOGY ELISAS

VIRAL GASTROENTERITIS

Premier® Adenoclone®
ELISA for the direct detection of adenovirus antigens in human stool samples as well as for the confirmation of adenovirus in cell culture.

This qualitative ELISA can be used for the direct detection of adenovirus antigens in human stool samples. In addition, the kit is suitable for the confirmation of adenovirus in cell culture isolates from respiratory, ophthalmic and gastrointestinal samples.

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Premier® Adenoclone® 40/41

A qualitative ELISA for the detection of adenovirus serotypes 40 and 41 in human stool samples.

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Premier® Rotaclone®

A qualitative ELISA for the detection of rotavirus antigen in human stool samples.

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VIROLOGIE Rapid TEST

VIRALE GASTROENTERITIS / RAPID TESTS

Meridian Bioscience Europe offers the following rapid test in the proven ImmunoCard® format:

ImmunoCard STAT!® Rota-Adeno-Noro2

A rapid in vitro rapid test for the qualitative detection (in separate test lines) of the antigens of rotavirus, adenovirus and norovirus genogroup I (GI) and genogroup II (GII) in human stool samples. A positive control is available separately for the test.

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VIROLOGIE IFT/DFT

Some pathogens can still be detected excellently using indirect or direct immunofluorescence (IFT / DFT) tests. We offer an extensive range of products from our longstanding partner company BIOS GmbH, in the following parameters / viruses using IFT and DFT:

  • Biognost® Adenovirus AK und AG
  • Biognost® Coxsackie Virus A AK
  • Biognost® Coxsackie Virus B AK
  • Biognost® Echovirus AK
  • Biognost® EBV-VCA AK
  • Biognost® EBV-EA „diffus“ und „restricted“ AK
  • Biognost® EBV-EBNA AK ACIF
  • Biognost® Herpes Simplex Virus 1 (HSV 1) AK
  • Biognost® Herpes Simplex Virus 2 (HSV 2) AK
  • Biognost® Human Herpes Virus 6 (HHV 6) AK
  • Biognost® Influenza Virus A AK
  • Biognost® Influenza Virus B AK
  • Biognost® Masern (Rubeola) Virus AK
  • Biognost® Mumps Virus AK
  • Biognost® Parainfluenza Virus 1 AK
  • Biognost® Parainfluenza Virus 2 AK
  • Biognost® Parainfluenza Virus 3 AK
  • Biognost® Parvovirus B19 AK
  • Biognost® Respiratory syncytial Virus (RSV) AK und AG
  • Biognost® Varizella zoster (VZV) AK und AG

All of these products are available as complete kits, including slides, conjugate, controls and buffer, or as individual components.

For the complete range of BIOS GmbH products, please visit our webshop.

 

PARASITOLOGY

STOOL TRANSPORT SYSTEMS

Meridian Bioscience Europe offers an extensive range of stool vessels. These are used for transport, stool concentration, fixation, optimal handling and diagnosis of parasites. There are also color solutions in the palette for optimal coloring of the parasites from fixed stool samples.

The brand names are: Para-Pak®, EcoFix® (mercury-free), EcoStain®, ®Con-Trate, SpinCon®

For the complete range of Meridian Bioscience products, please visit our webshop.

PARASITES ELISAS

CoproELISA™ kits from Savyon Diagnostics are a panel of enzyme immuno-tests for simultaneous or separate detection of gastrointestinal single-cell parasites directly from human stool samples.

  • Blastocystis
  • Giardia lamblia
  • Cryptosporidium
  • Entamoeba histolytica / dispar

Benefits:

  • Accuracy, high sensitivity & specificity (90-100%)
  • Compatible with fresh as well as formol and SAF-fixed samples
  • Modular billable plates for low, medium and high sample numbers
  • Minimal exposure to the sample - risk of contamination minimized
  • User friendly
  • Easy interpretation of the results - including cut-off control
  • Compatible with automation

 

For the complete range of Savyon Diagnostics products, please visit our webshop.

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PARASITOLOGY RAPID TESTS

From the company Savyon Diagnostics we perform the following rapid tests for parasite diagnostics.

The recently developed CoproStrip™ test cassettes from Savyon are chromatographic immunoassays for the qualitative detection of Cryptosporidium and / or Giardia antigens directly from human stool samples as an aid to the diagnosis of cryptosporidiosis and giardiasis.

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Benefits:

  • New design for the cassette format
  • Clear visual results; Green / red / blue colored test / control lines
  • High sensitivity and specificity
  • Sample tubes included
  • Results in minutes

Performance data:

Specificity

Sensitivity

Product name

>99%

>99%

CoproStripTM Giardia

>99%

>99%

CoproStripTM Cryptosporidium

>99%

   98%

CoproStripTM Giardia/Cryptosporidium

We offer the following rapid tests from Meridian Bioscience:

ImmunoCard STAT!® Crypto/Giardia
A qualitative rapid test for the detection of Cryptosporidium parvum and Giardia lamblia specific antigens.

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ImmunoCard STAT!® CGE

A qualitative rapid test for the detection of Cryptosporidium parvum, Giardia lamblia & Entamoeba histolytica.
A simple, fast and efficient test that can be stored at room temperature. Test results in 10 minutes. Accelerates the process of therapy decision and pathogen control. An external positive control is also available.

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Specificity

Sensitivity

Parameter

96,9 %**

80 %*

Cryptosporidium parvum

98,6 %**

92,4 %*

Giardia lamblia

89,8 %*

 75 %*

Entamoeba histolytica

 *  compared to PCR
** compared to microscopy

For the complete range of Savyon Diagnostics and Meridian Bioscience please visit our webshop.

 

PARASITOLOGY / IMMUNE FLUORESCENCE (IFT)

Some pathogenic parasites and protozoa can still be detected excellently using indirect or direct immunofluorescence (IFT / DFT) tests. For this we offer an extensive range of products from our long-standing partner company BIOS GmbH for the following parameters - verification by means of IFT / DFT:

All of these products are available as complete kits, including slides, conjugate, controls and buffer, or as individual components.

 

We offer the following immunofluorescence combination test from Meridian Bioscience:

Leishmania donovani

MERIFLUOR® Cryptosporidium/Giardia

This IFT is used to detect Cryptosporidium oocysts and Giradia cysts in stool samples.

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For the complete range of BIOS GmbH and Meridian Bioscience please visit our webshop.

 

FUNGAL INFECTIONS

For the diagnosis of fungal infections, we offer several methods from our partner company Meridian Bioscience.

The methods vary from ELISA, direct and indirect immunofluorescence and latex agglutination to double immunodiffusion according to Ouchterlony.

The following ELISA kits:

Premier®Cryptococcal Antigen
EIA for the detection of cryptococcal antigen in serum and liquor.

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Premier®Coocidiodes
A qualitative EIA for the detection of IgG and IgM antibodies against the 'TP' and 'CF' antigens of Coocidiodes immitis in serum and liquor.

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The following DFT kit:

MERIFLUOR® Pneumocystis
A direct immunofluorescence test for the detection of Pneumocystis carinii cysts and trophozoites in respiratory samples.

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Latex-agglutination:

CALAS® - Cryptococcal Antigen Latex Agglutination System
For the detection of cryptococcal antigen in serum and liquor.

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The following parameters with immunodiffusion:

  • Histoplasm
  • Coccidiodes
  • Aspergillus fumigatus
  • Blastomyces dermatitides

For the complete range of Meridian Bioscience products, please visit our webshop.