Corynoline, CAS 18797-79-0

Product Description: Corynoline is a reversible and noncompetitive acetylcholinesterase (AChE) inhibitor with an IC50 of 30.6 μM[1]. Corynoline exhibits anti-inflammatory activity by activating Nrf2[2].

Applications: COVID-19-immunoregulation

Formula: C21H21NO5

References: [1]Kim DK. Inhibitory effect of corynoline isolated from the aerial parts of Corydalis incisa on the acetylcholinesterase. Arch Pharm Res. 2002 Dec;25(6):817-9./[2]Liu B, et al. Corynoline Exhibits Anti-inflammatory Effects in Lipopolysaccharide (LPS)-Stimulated Human Umbilical Vein Endothelial Cells through Activating Nrf2. Inflammation. 2018 Oct;41(5):1640-1647.

CAS Number: 18797-79-0

Molecular Weight: 367.40

Compound Purity: 99.12

Research Area: Inflammation/Immunology; Neurological Disease; Cancer

Solubility: DMSO : 41.67 mg/mL (ultrasonic)

Target: Cholinesterase (ChE);Keap1-Nrf2

• SKU: MEXHY-N0826-10.1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-N0826-10.1
• Package Unit: 10 mM/1 ml
• Quantity Unit: STK