Cotransin, CAS 863753-73-5

Description: Cotransin, a Sec61 translocation inhibitor, selectively prevents the stable insertion of certain nascent chains into the Sec61 translocation channel, exhibiting signal-sequence discrimination. This compound also inhibits the expression of VCAM-1 and p-selectin proteins by blocking their co-translational translocation across endoplasmic reticulum (ER) membranes (IC 50 =0.5-5 µM). Cotransin's role extends to potential applications in inflammation and immunity research [1] [2].

CAS Number: 863753-73-5

Formula: C42H68N6O8

Molecular Weight: 785,02

• SKU: TGMTP2563-10mg
• Manufacturer: TargetMol Chemicals
• Manufacturer SKU: TP2563-10mg
• Package Unit: 10 mg
• Quantity Unit: STK