Product Description: CP 376395 is a potent, selective, and brain-penetrable Corticotropin releasing factor 1 (CRF1) receptor antagonist[1][2].
Applications: Neuroscience-Neuromodulation
Formula: C21H30N2O
References: [1]Chen YL, et al. 2-aryloxy-4-alkylaminopyridines: discovery of novel corticotropin-releasing factor 1 antagonists. J Med Chem. 2008 Mar 13;51(5):1385-92./[2]Giardino WJ, et al. CRF1 receptor signaling regulates food and fluid intake in the drinking-in-the-dark model of binge alcohol consumption. Alcohol Clin Exp Res. 2013 Jul;37(7):1161-70.
CAS Number: 175140-00-8
Molecular Weight: 326.48
Compound Purity: 99.68
Research Area: Neurological Disease; Endocrinology
Solubility: DMSO : ≥ 100 mg/mL
Target: CRFR