CP-544439, CAS 230954-09-3

Product Description: CP-544439 is a potent and orally active matrix metalloproteinase-13 (MMP-13) inhibitor with an IC50 of 0.75 nM[1][2].

Applications: COVID-19-immunoregulation

Formula: C18H19FN2O6S

References: [1]Dalvie D, et al. Metabolism distribution and excretion of a matrix metalloproteinase-13 inhibitor, 4-[4-(4-fluorophenoxy)-benzenesulfonylamino]tetrahydropyran-4-carboxylic acid hydroxyamide (CP-544439), in rats and dogs: assessment of the metabolic profile of CP-544439 in plasma and urine of humans. Drug Metab Dispos. 2008;36(9):1869-1883./[2]Reiter LA, et al. Pyran-containing sulfonamide hydroxamic acids: potent MMP inhibitors that spare MMP-1. Bioorg Med Chem Lett. 2004;14(13):3389-3395.

CAS Number: 230954-09-3

Molecular Weight: 410.42

Research Area: Inflammation/Immunology

Solubility: 10 mM in DMSO

Target: MMP

• SKU: MEXHY-107013-5
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-107013-5
• Package Unit: 5 mg
• Quantity Unit: STK