CP 673,451, CAS 343787-29-1

Shelf life (days): 1460.0

Formulation: A crystalline solid

Formal Name: 1-[2-[5-(2-methoxyethoxy)-1H-benzimidazol-1-yl]-8-quinolinyl]-4-piperidinamine

Purity: ≥98%

Formula Markup: C24H27N5O2

Formula Weight: 417.5

CAS Number: 343787-29-1

Notes: CP-673,451 is a selective inhibitor of the platelet-derived growth factor receptor β (PDGFRβ) kinase with an IC50 value of 1 nM.{30922} It also inhibits the PDGFRα kinase (IC50 = 10 nM), but exhibits greater than 450-fold selectivity over other angiogenic receptors such as VEGFR 2, TIE-2, and FGR2.{30922} In several in vivo tumor models, CP-673,451 has antiangiogenic and antitumor activity.{30922,30923,30921}

• SKU: CAY19170-5
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 19170-5
• Package Unit: 5 mg
• Quantity Unit: STK