CP-EPS8-NLS (trifluoroacetate salt)

Shelf life (days): 1460.0

Formulation: A solid

Amino Acids: Ac-GRKKRRQRRRPPQSKRKKGKKGKRK-NH2

Purity: ≥95%

Formula Markup: C135H256N62O30 / XCF3COOH

Formula Weight: 3227.87702

Notes: A cell-penetrating peptide inhibitor of EPS8 nuclear translocation; induces apoptosis and cell cycle arrest in the G0/G1 phase in THP-1, HL-60, and U937 cells at 70 µM; reduces phosphorylated ERK, STAT3, and Akt levels in THP-1, HL-60, and U937 cells at 35 or 70 µM; reduces tumor volume without affecting body weight in a U937 mouse xenograft model at 55 mg/kg every other day; decreases tumor volume alone or in combination with daunorubicin in a KG-1 AML mouse xenograft model at 50 mg/kg every other day

• SKU: CAY41743-1
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 41743-1
• Package Unit: 1 mg
• Quantity Unit: STK